FRAME, project funded by the European Commission, has developed models and empirical evidence to better understand a wide set of issues related to technology, macroeconomics, innovation, asset prices, labour markets and unemployment. The project has developed new Dynamic Stochastic General Equilibrium (DSGE) models and has generated new data in both multi-sector and multi-country settings that will allow for realistic estimates of the impact of public research and innovation activities on innovation, productivity growth and employment. New results have also been generated in terms of TFP estimators with the aim of being of help to academics and policymakers in understanding the impact on monetary and fiscal policy, technological adoption, asset pricing and innovation policy. Through this conference we will aim to understand how monetary and fiscal policymaking and the development of innovation policy for the diffusion of technology are interdependent in the short, medium and long-term.