Martin Ellison, Andrew Scott, David A. Sinclair, 11 August 2021

The majority of children born in high-income countries today can expect to live into old age, making ageing well an important priority. This column calculates that there are diminishing returns to further improvements in US life expectancy, and that it is more valuable to achieve a compression of morbidity. Treatments that delay ageing in ways that improve both health and life expectancy are especially valuable. Targeting ageing rather than single diseases exploit the synergies between health and lifespan, impacts several disease categories, and reduces competing risks. A virtuous circle in ageing leads to a rising value of delaying ageing the more we succeed in delaying ageing. 

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